
General Knowledge Scope for All Applicants
The scope of issues within the discipline of Biomedical Engineering. Key concepts: biocybernetic model, simulation of biological systems, and examples of their application in selected problems in biology and medicine. The role of biocybernetics and engineering in the development of technology, biology, medicine, and civilizational progress. Knowledge representation methods. The concept of incomplete and uncertain knowledge. Expert systems. Inference rules in rule-based knowledge representation systems. Fuzzy logic, evolutionary algorithms. Biomedical engineering systems in applications such as diagnostics, therapy, rehabilitation, and prosthetics of various organs and body parts—examples and general principles of their design.
Domain-Specific Scope I: Electronics and Informatics in Medicine
Fundamentals of theoretical neurocybernetics, various objectives and methods for brain modeling, different types of neural networks and their applications, elements of cognitive science. Models of biological and technical perceptual systems (human visual and auditory systems), regulatory systems (concept of homeostasis and the structure of systems that maintain it), and control systems (voluntary movement control, control of motor units and the gamma loop, cooperation of synergistic and antagonistic muscles). Population models. Computational methods for biomedical signal processing, as well as techniques for medical image analysis and recognition. Selected issues of artificial intelligence in biomedical applications. Methods used in biological and physiological measurements: monitoring of circulation, muscle tension, fetal well-being, brain function, and visual and auditory perception. Examples of digital support for signal and image diagnostics. Multidimensional and multimodal signals. Feature extraction and object/event classification methods. Human monitoring in domestic settings, taxonomy and specific characteristics of sensors. Sensor networks for biomedical measurements. Data security and privacy issues in medical networks and measurements. Hospital information systems, surgical planning, automated/remote patient qualification. Telemedicine challenges: data privacy and reliability, continuity of information access, mobility and energy considerations of devices. Brain-computer interfaces: BCI paradigms and their specific features.
Domain-Specific Scope II: Biomaterials Engineering
Basic concepts: biomaterial, biocompatibility, bioactivity, medical device, implant, transplant, artificial organ, hybrid organ. The relationship between the structure, properties, and methods of obtaining metallic, polymeric, ceramic, and composite biomaterials. Classification of biomaterials by: type (metallic, ceramic, polymeric, carbon-based, composite, hybrid) and their behavior in biological environments (biostable, degradable, resorbable). Practical applications of metallic, polymeric, carbon-based, composite biomaterials, phosphate-calcium bioceramics, and bioactive glasses, e.g., in surgery, orthopedics, cardiac surgery, and dentistry. Surface engineering and surface modification techniques. Methods for analyzing the structure, microstructure, and properties of biomaterials. Biological response to implants. In vitro and in vivo testing methods for biomaterials.
Domain-Specific Scope III: Biomechanics
Basic concepts: biomechanics and mechanobiology. Objectives and research directions in biomechanics. The relationship between structure and functional properties of tissues. Branches of biomechanics. Joint classification based on motion types. Biotribology and issues related to wear of joints and tissues. Structure and mechanical properties of bones. Models describing the mechanical behavior of bones. Functions and properties of articular cartilage, cartilage modeling. Structure and properties of connective tissues exemplified by tendons. Models describing tendon properties. Structure and function of the spine. Natural and synthetic biomaterials. Modeling of biomaterials as viscoelastic elements. Experimental methods used in tissue biomechanics (including stress, strain, displacement measurements, etc.). Fundamentals of mechanical strength of biological tissues—tensile, compressive, bending, and torsional strength.
1. Apatites as Geological and Planetary Minerals
Structural and chemical characteristics of apatites, mechanisms of isomorphic substitution, and the significance of apatites as indicators of magmatic, hydrothermal, diagenetic, and biological processes. Occurrence of apatites in terrestrial and extraterrestrial materials.
2. Microorganism–Mineral Interactions and Biomineralisation Processes
Mechanisms of biomineralisation, biodeterioration, and biologically mediated mineral transformation. The role of microorganisms in the cycling of phosphorus, iron, and other elements in natural and extreme environments.
3. Methods for the Investigation of Minerals, Rocks, and Geochemical Processes in Planetary Research
Capabilities and limitations of contemporary analytical methods applied in mineralogy, geochemistry, and geomicrobiology. Interpretation of mineralogical and geochemical data in the context of alteration, weathering, and biologically influenced processes.
4. Weathering Processes of Minerals and Rocks Across the Solar System
Comparison of physical, chemical, and radiation-induced weathering processes on Earth, Mars, the Moon, and small Solar System bodies. The influence of atmosphere, water activity, radiation, and temperature fluctuations on regolith transformation.
5. Lunar and Martian Regolith: Composition, Properties, and Transformation Processes
Mineralogical and geochemical characteristics of lunar and Martian regolith. Processes responsible for regolith formation and transformation, and the significance of regolith as an environment for geochemical and biological processes.
6. Lunar and Martian Regolith Simulants
Types of regolith simulants, methods of their production, and the degree to which they reproduce the properties of natural planetary materials. Opportunities and limitations associated with the use of simulants in geochemical, biological, and materials research.
7. Geochemical and Biological Processes in Extraterrestrial Environments and Space Habitats
The influence of microgravity, radiation, limited water availability, and regolith dust on geochemical processes and microbial activity. The importance of biological and mineral processes in closed-loop life support systems.
8. Methods for the Detection of Minerals and Alteration Processes on Planetary Bodies
Contemporary remote sensing and in situ analytical methods used in planetary exploration. Possibilities for identifying secondary minerals, products of aqueous alteration, and geochemical transformation processes using orbital and laboratory-derived data.